Administration details.
How to take Apixaban.
Apixaban is taken in the form of a tablet and ingested through the mouth with or without food(1).
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The dosage of Apixaban depends on what it is treating, although it is usually taken twice a day(1). Taking the correct dosage is important due to the associated risk factors.
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What are risk factors?
Risk factors are things to consider when prescribing a drug. They can impact the way the drug works and increase the likelihood of unwanted side effects(6).
The doctor will always way up the pros and cons of the drug before prescribing, so always listen to the doctor.
If you have any questions or concerns ask a pharmacist who can either answer your questions or help keep your mind at ease, or refer you to the appropriate people or resources.
Aged 80 or over - increased risk of bleeding(6)
Weigh 60kg or less - increased risk of bleeding(6)
Risk factors for Apixaban
Liver disease - increased risk of bleeding(6)
Dosage for specific health conditions can be seen below:
Dosage for the management of(6):
Deep vein thrombosis or pulmonary embolism:
10mg twice a day for 7 days, then 5mg twice a day
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Why take Apixaban over Warfarin?
Warfarin is also known as an anticoagulant and is used to thin the blood, similar to Apixaban. However, studies have shown that neither one is superior in treating or preventing disease(7,8). Some studies have shown that Apixaban has a reduced risk of bleeding(7,8), although many factors may effect this and it is important to listen to your doctors advice. If you have any queries contact your pharmacist.
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If you're interested in reading more, here are some scientific papers available to read:
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Risks of post-colonoscopic polypectomy bleeding and thromboembolism with warfarin and direct oral anticoagulants: a population-based analysis
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